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Not for use in diagnostic procedures.Starting today, most apt operations started crashing to the extent that I can't even run ubuntu-bug apt. This product is not available for sale in Japan.SIMILARITY: SwissProt: Q9UBU3 # Belongs to the motilin family. & Amidation of Leu-98 is essential for obestatin activity (By similarity). A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid.

The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy. TISSUE SPECIFICITY: Highest level in stomach. May reduce gastric emptying activity and jejunal motility (By similarity). May have an appetite-reducing effect resulting in decreased food intake. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.įUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin.

Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR MIM 601898) and is involved in regulating growth hormone (GH MIM 139250) release. Human Ghrelin (active) 100% Des-Octanoyl Human Ghrelin not detectable Canine Ghrelin (active) 106% Porcine Ghrelin (active) 57% Motilin Related Peptide (Human, Rat/Mouse) not detectable PYY 3-36 (Human, Mouse, Porcine) not detectable NPY (Human/Rat) Room temperature, 3 hour assay, 20 μL sample size (serum or plasma) This Human Ghrelin (active) ELISA is used to measure & quantify Ghrelin (active) levels in Metabolism & Endocrine & Neuroscience research. Key Specifications Table Analytes AvailableĬirculating ghrelin is a multifunctional hormone secreted primarily by the stomach.